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Harnessing a Revolution in Biology for Human Health®

Alnylam is the leading RNAi therapeutics company. We are a U.S.-based biopharmaceutical company with operations around the world. Founded in 2002 on a bold vision to turn Nobel Prize-winning science into an entirely new class of medicines, Alnylam has worked tirelessly for 20 years to turn the scientific possibility of RNAi into therapeutic reality. We believe that our efforts have the potential to improve the lives of patients worldwide who are waiting for new treatment options.

Areas of Therapeutic Focus

We have a robust pipeline of investigational RNAi therapeutics which is focused on diseases with high unmet medical needs that fall into 4 Strategic Therapeutic Areas (STArs): genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

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“Challenge Accepted” is our manifesto and the rallying cry that unites everyone who works at Alnylam. Many said RNAi therapeutics would never become reality. Many regard the diseases we are working to treat – which either have no treatment options or the ones that exist are inadequate – as “undruggable.” We disagree on both counts. We believe that the unique characteristics of RNAi mean that RNAi therapeutics have the potential to change the way that medicine treats disease. Because no patient should have to wait for hope, we accept the challenges inherent in ambitious scientific discovery and the difficult work of developing an entirely new class of medicines.

Mission, Vision, and Values

Alnylam was founded on a revolutionary vision and bold mission, which remain firmly in place today. We are a growing biopharmaceutical company developing novel therapeutics based on RNAi.

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Our Vision

Harness the power of RNAi to change the way medicine treats disease.

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Our Mission

Build a top-tier, global, independent biopharmaceutical company founded on RNAi.

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Our Core Values

Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture and Passion for Excellence.


Alnylam has assembled a diverse team of passionate leaders from across the biopharmaceutical industry and across the globe. Together, they possess vast experience in drug discovery, drug development, and global commercialization.

Diversity & Inclusion

At Alnylam, we believe that our long-term success and ability to deliver medicines to patients requires a diverse and inclusive workforce.

We are committed to building an environment where employees are enabled to achieve their full potential. By empowering employees to bring their unique differences to work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

We promote an environment of diversity and inclusiveness at Alnylam, regardless of race, gender, sexual orientation, religion, ethnicity, national origin, physical disability, or age.

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Our Culture

We strongly believe in the power of a positive culture as a key differentiator for individual and business success. That is why we are so proud of winning a spot on the Boston Globe’s “Top Places to Work” the last seven years in a row.

Our employees come from a diverse background, representing dozens of countries and more than 20 languages. What is common to all Alnylam-ites is turning our passion for helping patients into concrete actions by leveraging the strengths of all.

We have strong values that guide who we hire, what we recognize, what we value, and that serve as the foundation of our culture.

  • Passion for Excellence
  • Innovation and Discovery
  • Commitment to People
  • Open Culture
  • Sense of Urgency

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